- ￥1500
- Bioss
- bs-0601P
- 2025年10月16日
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500ug
| 产品编号 | bs-0601P |
| 英文名称 | PACAP (1-38) Active Peptide |
| 中文名称 | 腺苷酸环化酶激活肽 (1-38) 活性多肽 |
| 英文别名 | HSPC190; Proapoptotic Caspase Adaptor Protein; PACAP; pERp1; Plasma cell-induced ER protein 1; Plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; Proapoptotic caspase adapter protein; pituitary adenylate cyclase activating polypeptide; PRP-48; PACAP-related peptide; Pituitary adenylate cyclase-activating polypeptide 38; Pituitary adenylate cyclase-activating polypeptide 38; PACAP38; PACAP-38; PACA_HUMAN. |
| 中文别名 | 垂体腺苷酸环化酶激活多肽-38; |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Cell Biology > Apoptosis > Intracellular > Caspases etc > Caspases Neuroscience > Neurotransmitter > Neuropeptides > Hormones |
| 亚基 | Interacts with ADCYAP1R1 (via N-terminal extracellular domain). |
| 亚细胞定位 | Extracellular region or secreted |
| 相似性 | Belongs to the glucagon family. |
| 功能 | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] |
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PACAP (1-38) Active Peptide(bs-0601P)-500ug
￥1500
