- ￥880
- Bioss
- bs-14270P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14270P |
| 英文名称 | DENND1C Antibody Blocking Peptide |
| 中文名称 | DENND1C蛋白封闭多肽 |
| 英文别名 | Connecdenn 3; DEN1C_HUMAN; DENN domain-containing protein 1C; Dennd1c; FAM31C; FLJ22757; Protein FAM31C. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚基 | Exhibits low nucleotide-independent RAB35-binding activity. Interacts with clathrin heavy chain/CLTC and with AP2A2, but not with AP2B1. |
| 亚细胞定位 | Cytoplasm; cytosol. Cytoplasmic vesicle; clathrin-coated vesicle. |
| 相似性 | Contains 1 dDENN domain. Contains 1 DENN domain. Contains 1 uDENN domain |
| 功能 | Guanine nucleotide exchange factor (GEF) for RAB35 |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
DENND1C Antibody Blocking Peptide(bs-14270P)-500ug
￥880
