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500ug
| 产品编号 | bs-13719P |
| 英文名称 | EPB41L5 Antibody Blocking Peptide |
| 中文名称 | 红细胞膜蛋白条带EPB41L5封闭多肽 |
| 英文别名 | Band 4.1-like protein 5; BE37; E41L5_HUMAN; Epb41l5; erythrocyte membrane protein band 4.1 like 5; KIAA1548. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with MPP5, CRB2 and CRB3. |
| 亚细胞定位 | Cytoplasm. Cell junction; adherens junction. Associated with the plasma membrane. Colocalizes with CTNNB1, an adherens junction marker. |
| 相似性 | Contains 1 FERM domain. |
| 功能 | May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. EPB41L5 (erythrocyte membrane protein band 4.1 like 5), also known as BE37 or YMO1, is a 733 amino acid cytoplasmic protein that contains one FERM domain, which it uses to bind CRB1 (crumbs homolog 1). EPB41L5 is a homolog of zebrafish 'mosaic eyes' (moe), and is widely expressed but found at highest levels in ovary, kidney and brain, and is known to colocalize with β-catenin. EPB41L5 may participate in tight junction positioning during the establishment of epithelial cell polarity, and exists as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 2q14.2. |
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EPB41L5 Antibody Blocking Peptide(bs-13719P)-500ug
¥880





