EPB41L5 Antibody Blocking Peptide(bs-13719P)-500ug

EPB41L5 Antibody Blocking Pept

ide(bs-13719P)-500ug
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  • ¥880
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  • bs-13719P
  • 2025年10月16日
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      500ug

    产品编号bs-13719P
    英文名称EPB41L5 Antibody Blocking Peptide
    中文名称红细胞膜蛋白条带EPB41L5封闭多肽
    英文别名Band 4.1-like protein 5; BE37; E41L5_HUMAN; Epb41l5; erythrocyte membrane protein band 4.1 like 5; KIAA1548.
    纯化方法HPLC
    亚基Interacts with MPP5, CRB2 and CRB3.
    亚细胞定位Cytoplasm. Cell junction; adherens junction. Associated with the plasma membrane. Colocalizes with CTNNB1, an adherens junction marker.
    相似性Contains 1 FERM domain.
    功能May contribute to the correct positioning of tight junctions during the establishment of polarity in epithelial cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. EPB41L5 (erythrocyte membrane protein band 4.1 like 5), also known as BE37 or YMO1, is a 733 amino acid cytoplasmic protein that contains one FERM domain, which it uses to bind CRB1 (crumbs homolog 1). EPB41L5 is a homolog of zebrafish 'mosaic eyes' (moe), and is widely expressed but found at highest levels in ovary, kidney and brain, and is known to colocalize with β-catenin. EPB41L5 may participate in tight junction positioning during the establishment of epithelial cell polarity, and exists as four alternatively spliced isoforms that are encoded by a gene located on human chromosome 2q14.2.

     

     

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