PCDHA4 Antibody Blocking Peptide(bs-11118P)-500ug

PCDHA4 Antibody Blocking Pepti

de(bs-11118P)-500ug
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  • ¥880
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  • bs-11118P
  • 2025年10月16日
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      500ug

    产品编号bs-11118P
    英文名称PCDHA4 Antibody Blocking Peptide
    中文名称原钙粘附蛋白α4封闭多肽
    英文别名CNR1; CNRN1; CRNR1; Ortholog of mouse CNR1; PCDA4_HUMAN; PCDH alpha 4; PCDH ALPHA4; PCDH-alpha-4; PCDHA 4; PCDHA4; Protocadherin alpha 4; Protocadherin alpha-4.
    纯化方法HPLC
    亚细胞定位Cell membrane.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Members of the cadherin-related neuronal receptor (CNR) family, including PCDHA4 (also known as CNR1) and PCDHA6 (also known as CNR2), comprise a novel subfamily within the cadherin superfamily of adhesion molecules. The cadherin-related neuronal receptor proteins form a complex with Fyn, a protein tyrosine kinase that is involved in building brain networks and determining patterns of behavior. Cadherin-related neuronal receptor 1 and 2 were discovered during a search for receptor molecules to the Fyn signaling pathway in the mammalian brain. Members of the cadherin superfamily are Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The PCDHA4 and PCDHA6 extracellular domains contain six cadherin repeats that mediate Ca++-dependent cell adhesion, while the cytoplasmic domains are not homologous with other cadherins.

     

     

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