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- bs-11103P
- 2025年10月16日
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500ug
| 产品编号 | bs-11103P |
| 英文名称 | Netrin G2 Antibody Blocking Peptide |
| 中文名称 | 轴突生长诱向因子G2/神经突起生长导向因子G2封闭多肽 |
| 英文别名 | Laminet 2; Laminet-2; Laminet2;Lmnt2; Lmnt 2; Lmnt-2; Netrin-G2; NetrinG2; NTNG1; NTNG 1; NTNG-1; NTNG2; NTNG 2; NTNG-2; NTNG2_HUMAN; bA479K20.1; LHLL9381. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins Neuroscience > Neurology process > Neurodegenerative disease Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with LRRC4 (By similarity). |
| 亚细胞定位 | Cell membrane. |
| 翻译后修饰 | N-glycosylated (By similarity). |
| 相似性 | Contains 3 laminin EGF-like domains.
Contains 1 laminin N-terminal domain. |
| 功能 | Promotes neurite outgrowth of both axons and dendrites. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor components, including deleted in colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient. |
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Netrin G2 Antibody Blocking Peptide(bs-11103P)-500ug
￥880
