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- bs-16831P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16831P |
| 英文名称 | KRT72 Antibody Blocking Peptide |
| 中文名称 | 细胞角蛋白72封闭多肽 |
| 英文别名 | CK-72; Cytokeratin-72; K2C72_HUMAN; K6irs; K6IRS2; K72; KB35; Keratin 6 inner root sheath 2; keratin protein K6irs; Keratin type II cytoskeletal 72; Keratin-72; KRT6; KRT6IRS2; Krt72; Type II inner root sheath-specific keratin-K6irs2; Type-II keratin Kb35. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class I > Cytokeratins |
| 亚基 | Heterotetramer of two type I and two type II keratins. |
| 组织特异性 | Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level). |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009] |
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KRT72 Antibody Blocking Peptide(bs-16831P)-500ug
￥880
