CDH8 Antibody Blocking Peptide(bs-11077P)-500ug

CDH8 Antibody Blocking Peptide

(bs-11077P)-500ug
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  • ¥880
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  • bs-11077P
  • 2025年10月16日
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      500ug

    产品编号bs-11077P
    英文名称CDH8 Antibody Blocking Peptide
    中文名称钙粘附蛋白8封闭多肽
    英文别名CADH8_HUMAN; Cadherin 8, type 2; Cadherin-8; CDH 8; CDH8; Putative protein product of Nbla04261.
    纯化方法HPLC
    研究领域

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚基Contains 5 cadherin domains.
    亚细胞定位Cell membrane.
    组织特异性Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts.
    相似性Contains 5 cadherin domains.
    功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function. Cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology.

     

     

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