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500ug
| 产品编号 | bs-11077P |
| 英文名称 | CDH8 Antibody Blocking Peptide |
| 中文名称 | 钙粘附蛋白8封闭多肽 |
| 英文别名 | CADH8_HUMAN; Cadherin 8, type 2; Cadherin-8; CDH 8; CDH8; Putative protein product of Nbla04261. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > Membrane Proteins Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins |
| 亚基 | Contains 5 cadherin domains. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts. |
| 相似性 | Contains 5 cadherin domains. |
| 功能 | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function. Cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology. |
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CDH8 Antibody Blocking Peptide(bs-11077P)-500ug
¥880







