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- Bioss
- bs-23278P
- 2025年10月16日
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500ug
| 产品编号 | bs-23278P |
| 英文名称 | Wnt3a Antibody Blocking Peptide |
| 中文名称 | 信号通路Wnt3a封闭多肽 |
| 英文别名 | MGC119418; MGC119419; MGC119420; Protein Wnt 3a Precursor; Protein Wnt-3a; Wingless type MMTV integration site family member 3A; Wnt 3a; WNT3A protein. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Embryogenesis > Morphogens Neuroscience > Neurology process > Neurogenesis Stem Cells > Signaling Pathways > Wnt > Secreted |
| 亚基 | Interacts with PORCN. Interacts with APCDD1 and WLS. Component of the Wnt-Fzd-LRP5-LRP6 signaling complex that contains a WNT protein, a FZD protein and LRP5 or LRP6. Interacts directly in the complex with LRP6. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matr |
| 组织特异性 | Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. |
| 翻译后修饰 | Palmitoylation at Ser-209 by PORCN is required for proper trafficking to cell surface, vacuolar acidification is critical to release palmitoylated WNT3A from WLS in secretory vesicles. |
| 相似性 | Belongs to the Wnt family. |
| 功能 | Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008] |
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Wnt3a Antibody Blocking Peptide(bs-23278P)-500ug
￥880
