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- bs-16733P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-16733P |
| 英文名称 | TRIM37 Antibody Blocking Peptide |
| 中文名称 | TRIM37蛋白封闭多肽 |
| 英文别名 | E3 ubiquitin protein ligase TRIM37; E3 ubiquitin-protein ligase TRIM37; KIAA0898; MUL; MUL protein; Mulibrey nanism gene; Mulibrey nanism protein; POB 1; POB1; RING B box coiled coil protein; TEF 3; TEF3; TRI37_HUMAN; TRIM 37; Trim37; Tripartite motif containing 37; Tripartite motif containing 37 protein; Tripartite motif containing protein 37; Tripartite motif-containing protein 37. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Ubiquitylation Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger |
| 亚细胞定位 | Cytoplasm > perinuclear region. Peroxisome. Found in vesicles of the peroxisome. Aggregates as aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomal degradation. |
| 组织特异性 | Ubiquitous. |
| 翻译后修饰 | Auto-ubiquitinated. |
| 相似性 | Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 MATH domain. Contains 1 RING-type zinc finger. |
| 功能 | E3 ubiquitin-protein ligase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TRIM37 is a protein that localizes to peroxisomes and contains a tripartite motif (TRIM) and a tumor necrosis factor-receptor associated factor (TRAF) domain. The protein and gene forms of TRIM37 are highly conserved between human and mouse. TRIM37 is expressed at a low level in the liver, ovary, heart, lung, skeletal muscle, and kidney, while it is highly expressed in the testis and brain, where it may act as an E3 ubiquitin ligase. Mutations in the TRIM37 gene result in Mulibrey nanism, an autosomal recessive prenatal-onset growth disorder that causes characteristic dysmorphic craniofacial features, heart disease, cardiopathy, failure of sexual maturation, and hepatomegaly. |
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TRIM37 Antibody Blocking Peptide(bs-16733P)-500ug
￥880
