- ￥880
- Bioss
- bs-12301P
- 2025年10月16日
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- 技术资料
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500ug
| 产品编号 | bs-12301P |
| 英文名称 | CDX4 Antibody Blocking Peptide |
| 中文名称 | 尾型同源盒转录因子4封闭多肽 |
| 英文别名 | Caudal-type homeobox protein 4; CDX4; CDX4_HUMAN; Homeobox protein CDX-4. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > HOX Stem Cells > Hematopoietic Progenitors > Intracellular Molecules |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the Caudal homeobox family. Contains 1 homeobox DNA-binding domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila “caudal” gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord. |
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CDX4 Antibody Blocking Peptide(bs-12301P)-500ug
￥880
