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- 规格:
10ug/50ug/100ug
| 规格: | 10ug | 产品价格: | ¥2980.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥9800.0 |
| 规格: | 100ug | 产品价格: | ¥18900.0 |
| 产品编号 | bs-48022P |
| 英文名称 | Recombinant human TPO protein (Active, HEK293) |
| 中文名称 | 重组人血小板生成素 (活性的, Tag free) |
| 英文别名 | Thrombopoietin; C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Myeloproliferative leukemia virus oncogene ligand; ML; MGDF; THPO; TPO-HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 实际分子量 | 80-85kDa |
| 浓度 | >0.5 mg/ml |
| 储存液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 研究领域 | Cancer > Cell cycle > Cell differentiation Cardiovascular > Blood > Fibrinolysis / Thrombolysis Cell Biology > Cell Cycle > Cell differentiation Stem Cells > Mesenchymal Stem Cells > Osteogenesis |
| 亚基 | Interacts with DUOX1, DUOX2 and CYBA. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Isoform 3: Cell surface. |
| 相似性 | Belongs to the peroxidase family. XPO subfamily.
Contains 1 EGF-like domain. Contains 1 Sushi (CCP/SCR) domain. |
| 功能 | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014] |

The purity of the protein is greater than 95% as determined by non reduced and reduced SDS-PAGE.
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Recombinant human TPO protein (Active, HEK293)(bs-48022P)-10ug/50ug/100ug
¥2980 - 18900





