Recombinant human TPO protein (Active, HEK293)(bs-48022P)-10ug/50ug/100ug

Recombinant human TPO protein

(Active, HEK293)(bs-48022P)-10ug/50ug/100ug
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  • ¥2980 - 18900
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  • bs-48022P
  • 2025年10月16日
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      10ug/50ug/100ug

    规格:10ug产品价格:¥2980.0
    规格:50ug产品价格:¥9800.0
    规格:100ug产品价格:¥18900.0
    产品编号bs-48022P
    英文名称Recombinant human TPO protein (Active, HEK293)
    中文名称重组人血小板生成素 (活性的, Tag free)
    英文别名Thrombopoietin; C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Myeloproliferative leukemia virus oncogene ligand; ML; MGDF; THPO; TPO-HUMAN.
    性状Lyophilized
    纯化方法AC
    实际分子量80-85kDa
    浓度>0.5 mg/ml
    储存液Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
    研究领域

    Cancer > Cell cycle > Cell differentiation

    Cardiovascular > Blood > Fibrinolysis / Thrombolysis

    Cell Biology > Cell Cycle > Cell differentiation

    Stem Cells > Mesenchymal Stem Cells > Osteogenesis

    亚基Interacts with DUOX1, DUOX2 and CYBA.
    亚细胞定位Membrane; Single-pass type I membrane protein. Isoform 3: Cell surface.
    相似性Belongs to the peroxidase family. XPO subfamily.
    Contains 1 EGF-like domain.
    Contains 1 Sushi (CCP/SCR) domain.
    功能Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
    保存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]

     

     

    Recombinant human TPO protein
    The purity of the protein is greater than 95% as determined by non reduced and reduced SDS-PAGE.

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