- ￥880
- Bioss
- bs-14410P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14410P |
| 英文名称 | DOP1B Antibody Blocking Peptide |
| 中文名称 | 迟钝蛋白家族2封闭多肽 |
| 英文别名 | 21orf5; Dopey-2; C21orf5; DOP2_HUMAN; Dopey family member 2; DOPEY2; homolog of yeast DOP1; Protein dopey-2. |
| 纯化方法 | HPLC |
| 组织特异性 | Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients. |
| 相似性 | Belongs to the dopey family. |
| 功能 | May be involved in protein traffic between late Golgi and early endosomes. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Dopey-2 is a 2,298 amino acid protein that is ubiquitously expressed with high levels found in the developing central nervous system where it is thought to play a role in protein trafficking between early endosomes and the late Golgi. Multiple isoforms of Dopey-2 exist due to alternative splicing events. The gene encoding Dopey-2 maps to human chromosome 21 and may be involved in the pathogenesis of Down syndrome. The smallest of the human chromosomes, chromosome 21 comprises about 1.5% of the human genome and contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. |
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DOP1B Antibody Blocking Peptide(bs-14410P)-500ug
￥880
