- ￥880
- Bioss
- bs-11433P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-11433P |
| 英文名称 | DUOXA1 Antibody Blocking Peptide |
| 中文名称 | 双氧化酶成熟因子封闭多肽 |
| 英文别名 | DOXA1_HUMAN; Dual oxidase activator 1; Dual oxidase maturation factor 1; duoxa1; NIP; Numb interacting protein; Numb-interacting protein; NUMBIP. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Endocrine system > Thyroid axis |
| 亚基 | May interact with NUMB. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein |
| 组织特异性 | Specifically expressed in thyroid gland. Also detected in esophagus. |
| 相似性 | Belongs to the DUOXA family. |
| 功能 | May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DUOXA1 is a 343 amino acid multi-pass membrane protein that belongs to the DUOXA family and exists as multiple alternatively spliced isoforms. Expressed almost exclusively in thyroid tissue, but also present in esophageal tissue, DUOXA1 interacts with NUMB and is thought to be essential for the maturation and transport of functional DUOX1 from the endoplasmic reticulum to the plasma membrane. The gene encoding DUOXA1 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
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DUOXA1 Antibody Blocking Peptide(bs-11433P)-500ug
￥880
