- ￥880
- Bioss
- bs-13158P
- 2025年10月16日
企业认证
相关产品推荐更多 >
TRAF7 Antibody Blocking Peptide(bs-7676P)-500ug
￥880PCDHB12 Antibody Blocking Peptide(bs-13732P)-500ug
￥880Collagen II/Chondrocalcin Antibody Blocking Peptide(bs-10589P)-500ug
￥880
phospho-HSF1( Ser326) Antibody Blocking Peptide(bs-3745P)-500ug
￥1080AP2 alpha + beta Antibody Blocking Peptide(bs-12480P)-500ug
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13158P |
| 英文名称 | FHOD1 Antibody Blocking Peptide |
| 中文名称 | 肢体畸形相关蛋白FHOD1封闭多肽 |
| 英文别名 | FH1/FH2 domain containing protein; FH1/FH2 domain-containing protein 1; Fhod1; FHOD1_HUMAN; FHOS; FHOS1; Formin homolog overexpressed in spleen 1; Formin homology 2 domain containing 1; Formin homology 2 domain containing protein 1; Formin homology 2 domain-containing protein 1. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins |
| 亚基 | Self-associates via the FH2 domain. Binds to F-actin via its N-terminus. Binds to the cytoplasmic domain of CD21 via its C-terminus. Interacts with ROCK1 in a Src-dependent manner. |
| 亚细胞定位 | Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic. |
| 组织特异性 | Ubiquitous. Highly expressed in spleen. |
| 翻译后修饰 | Phosphorylated by ROCK1. |
| 相似性 | Belongs to the formin homology family. Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. |
| 功能 | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
FHOD1 Antibody Blocking Peptide(bs-13158P)-500ug
￥880
