- ￥880
- Bioss
- bs-7676P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7676P |
| 英文名称 | TRAF7 Antibody Blocking Peptide |
| 中文名称 | 肿瘤坏死因子受体相关因子7封闭多肽 |
| 英文别名 | E3 ubiquitin protein ligase TRAF7; RFWD1; Ring finger and WD repeat domain 1; RING finger protein 119; RNF119; TNF receptor associated factor 7; TRAF7_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Homodimer. Interacts with MAP3K3 and promotes the kinase activity of this enzyme. |
| 亚细胞定位 | Colocalizes with MAP3K3 to vesicle like structures throughout the cytoplasm. |
| 组织特异性 | Ubiquitously expressed with high levels in skeletal muscle, heart, colon, spleen, kidney, liver and placenta. |
| 翻译后修饰 | Phosphorylated by MAP3K3. Ubiquitinates itself upon phosphorylation. |
| 相似性 | Belongs to the WD repeat TRAF7 family. Contains 1 RING-type zinc finger. Contains 1 TRAF-type zinc finger. Contains 7 WD repeats. |
| 功能 | E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TNF receptor associated factor 7 (TRAF7) is an E3 ubiquitin ligase capable of auto ubiquination, following phosphorylation by MAP3K3. TRAF7 potentiates MEKK3 mediated activation of the NFkappaB, JUN/AP1 and DDIT3 transcriptional regulators. TRAF7 induces apoptosis when over expressed. |
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TRAF7 Antibody Blocking Peptide(bs-7676P)-500ug
￥880
