Phospho-NMDAR2A (Tyr1246) Antibody Blocking Peptide(bs-3304P)-500ug

Phospho-NMDAR2A (Tyr1246) Anti

body Blocking Peptide(bs-3304P)-500ug
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  • bs-3304P
  • 2025年10月16日
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      500ug

    产品编号bs-3304P
    英文名称Phospho-NMDAR2A (Tyr1246) Antibody Blocking Peptide
    中文名称磷酸化谷氨酸受体2A封闭多肽
    英文别名NMDAR2A (phospho T1246) ; p-NMDAR2A (phospho T1246) ; GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A; hNR3; N methyl D aspartate receptor subtype 2A; N methyl D aspartate receptor subtype 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2A; NMDAR2B; NMDE2_HUMAN; NR2A; NR2B; NR3.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > NMDA Receptors

    亚基Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Found in a complex with GRIN1 and GRIN3B. Found in a complex with GRIN1, GRIN3A and PPP2CB. Interacts with PDZ domains of AIP1, INADL and DLG4. Interacts with HIP1 and NETO1 (By similarity). Interacts with LRFN2 (By similarity).
    亚细胞定位Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (By similarity).
    相似性Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily.
    功能NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

     

     

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