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- 2025年10月16日
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| 规格： | 10ug | 产品价格： | ￥2680.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥8800.0 |
| 规格： | 500ug | 产品价格： | ￥58000.0 |
| 产品编号 | bs-48008P |
| 英文名称 | Recombinant human IL-28A protein (Active, HEK293) |
| 中文名称 | 重组人白介素28A (活性的, Tag free) |
| 英文别名 | rhIL-28A; Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; rhIL-28A; EG330496; Ifnl2; IFNL2_HUMAN. ;Recombinant human IL-28A protein (Active, HEK293) |
| 中文别名 | 人白介素28A 重组蛋白; 人白细胞介素28A ; 重组人白介素28A; |
| 性状 | Lyophilized |
| 纯化方法 | AC |
| 理论分子量 | 24 |
| 实际分子量 | 17-38 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the lambda interferon family. |
| 功能 | Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] |
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