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500ug
| 产品编号 | bs-1190P |
| 英文名称 | ECE1 Antibody Blocking Peptide |
| 中文名称 | 内皮素转化酶1封闭多肽 |
| 英文别名 | ECE 1; ECE-1; Endothelin converting enzyme 1; ECE1_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Cardiovascular > Vasculature > Endothelium Cardiovascular > Vasculature > Vasoconstriction Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Cell Membrane. Single pass type II membrane protein. |
| 组织特异性 | All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. |
| 相似性 | Belongs to the peptidase M13 family. |
| 功能 | Converts big endothelin-1 to endothelin-1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]. |
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ECE1 Antibody Blocking Peptide(bs-1190P)-500ug
¥880







