- ￥880
- Bioss
- bs-9107P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9107P |
| 英文名称 | PYDC1 Antibody Blocking Peptide |
| 中文名称 | 感染性蛋白唯一蛋白1封闭多肽 |
| 英文别名 | PAAD domain only protein; POP1; PYDC1; Pyrin domain containing 1; Pyrin only protein 1; PYDC1_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚基 | Interacts with PYCARD/ASC. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Predominantly expressed in monocytes,macrophages and granulocytes. |
| 翻译后修饰 | Phosphorylated. |
| 相似性 | Contains 1 DAPIN domain. |
| 功能 | Associates with apoptosis-associated specklike proteincontaining a CARD domain (ASC) and modulates its ability tocollaborate with pyrin and cryopyrin in NF-kappa-B andpro-caspase-1 activation. Suppresses kinase activity of NF-kappa-Binhibitor kinase (IKK) complex, expression of NF-kappa-B induciblegenes and inhibits NF-kappa-B activation by cytokines and LPS. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The death domain (DD) superfamily of proteins share one or more of the following domains: the DD, DED (death-effector domain), CARD (caspase-recruitment domain) and PYD (Pyrin domain). Each of these domains is characterized by a canonical death domain fold, which consists of a bundle of five or six antiparallel α-helices. As their names suggest, these domains play prominent roles in programmed cell death. ASC2 (apoptosis-associated speck-like protein containing a CARD 2), also known as Pyrin-only protein 1 or PADD-only protein 1, is an 89 amino acid member of the DD superfamily that contains one Pyrin domain. Localized to the cytoplasm, ASC2 interacts with ASC to modulate NF-κB and pro-caspase-1 regulation. ASC2 is predominantly expressed in monocytes, macrophages and granulocytes. |
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PYDC1 Antibody Blocking Peptide(bs-9107P)-500ug
￥880
