- ￥880
- Bioss
- bs-21823P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-21823P |
| 英文名称 | OSMR Antibody Blocking Peptide |
| 中文名称 | 抑瘤素M受体封闭多肽 |
| 英文别名 | Oncostatin M receptor; Oncostatin M specific receptor subunit beta; Interleukin-31 receptor subunit beta; IL-31 receptor subunit beta; IL-31R subunit beta; IL-31R-beta; IL-31RB; Oncostatin-M-specific receptor, beta; OSMRB; MGC140467; MGC150626; MGC150627; MGC75127. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs Immunology > Innate Immunity > Cytokines > IL6 Related Immunology > Innate Immunity > Cytokines > Interleukins Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines. |
| 相似性 | Belongs to the type I cytokine receptor family. Type 2 subfamily.
Contains 4 fibronectin type-III domains. |
| 功能 | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. |
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OSMR Antibody Blocking Peptide(bs-21823P)-500ug
￥880
