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- Bioss
- bs-2500P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2500P |
| 英文名称 | IRF4 Antibody Blocking Peptide |
| 中文名称 | 干扰素调节因子4封闭多肽 |
| 英文别名 | Interferon regulatory factor 4; IRF 4; IRF4; IRF-4; LSIRF; Lymphocyte specific interferon regulatory factor; Multiple myeloma oncogene 1; MUM 1; NF EM5; NFEM5; OTTHUMP00000017905; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; Transcriptional activator PIP; IRF4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Transcription factors Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Interacts with the BATF-JUNB heterodimer. Interacts with BATF (via bZIP domain); the interaction is direct (By similarity). Interacts with SPIB and DEF6. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Lymphoid cells. |
| 翻译后修饰 | Phosphorylation by ROCK2 regulates IL-17 and IL-21 production (By similarity). |
| 相似性 | Belongs to the IRF family. Contains 1 IRF tryptophan pentad repeat DNA-binding domain. |
| 功能 | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. |
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IRF4 Antibody Blocking Peptide(bs-2500P)-500ug
￥880
