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500ug
| 产品编号 | bs-17053P |
| 英文名称 | KIF26A Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族成员26A封闭多肽 |
| 英文别名 | DKFZP434N178; FLJ22753; KI26A_HUMAN; KIAA1236; KIF 26A; KIF26A; KIF26A variant protein; Kinesin family member 26A; Kinesin like protein KIF26A; Kinesin-like protein KIF26A. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Kinesin-like |
| 亚细胞定位 | Cytoplasm > cytoskeleton. |
| 相似性 | Belongs to the kinesin-like protein family. KIF26 subfamily. Contains 1 kinesin-motor domain. |
| 功能 | Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF26A (kinesin family member 26A) is a 1,882 amino acid protein that contains one N-terminal kinesin-motor domain and belongs to the kinesin-like protein family. The kinesin-motor domain is responsible for the ATP-dependent movement of KIF26A across microtubules. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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