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- Bioss
- bs-15584P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15584P |
| 英文名称 | PLAC8 Antibody Blocking Peptide |
| 中文名称 | 胎盘特异基因8蛋白封闭多肽 |
| 英文别名 | C15; Onzin; PLAC8; PLAC8_HUMAN; Placenta specific 8; Placenta-specific gene 8 protein; Protein C15. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Placental development |
| 亚基 | |
| 组织特异性 | Expressed at high levels in plasmacytoid dendritic cells. High expression in spleen, lymph nodes, peripheral blood leukocytes, and bone marrow, with lower expression in thymus, appendix, and fetal liver. |
| 翻译后修饰 | |
| 相似性 | |
| 功能 | |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | PLAC8 is a 115 amino acid protein belonging to the cornifelin family that is expressed at high levels in plasmacytoid dendritic cells and other organs of the immune system including lymph nodes, spleen, bone marrow and peripheral blood leukocytes, with lower expression in appendix, thymus and fetal liver. Human PLAC8 shares 83% homology with murine PLAC8, where it has been identified in placenta from 9.5-18.5 days postcoitum. The gene encoding PLAC8 maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease |
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PLAC8 Antibody Blocking Peptide(bs-15584P)-500ug
￥880
