- ￥880
- Bioss
- bs-15575P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15575P |
| 英文名称 | IGKV2-29 Antibody Blocking Peptide |
| 中文名称 | kappa轻链可变区封闭多肽 |
| 英文别名 | IGKV A18; Kappa light chain variable region; Immunoglobulin kappa variable 2-29; A18; A18b; IGKV; IGKV229; IGVK-A18; immunoglobulin kappa variable 2-29 (gene/pseudogene); KV229_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked. |
| 亚细胞定位 | Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. |
| 功能 | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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IGKV2-29 Antibody Blocking Peptide(bs-15575P)-500ug
￥880
