HIGD1A Antibody Blocking Peptide(bs-9066P)-500ug

HIGD1A Antibody Blocking Pepti

de(bs-9066P)-500ug
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  • bs-9066P
  • 2025年10月16日
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      500ug

    产品编号bs-9066P
    英文名称HIGD1A Antibody Blocking Peptide
    中文名称缺氧诱导基因1蛋白/HIGD1A封闭多肽
    英文别名Hig1; HIG1 domain family member 1A; HIG1 domain family, member 1A; HIG1 hypoxia inducible domain family, member 1A; HIG1A_HUMAN; HIGD1A; HIMP1; Hypoxia-inducible gene 1 protein.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    亚基Associates with cytochrome c oxidase (COX, complex IV); proposed complex component. Also associates with respratory chain supercomplexes.
    亚细胞定位Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane (Probable).
    相似性Contains 1 HIG1 domain.
    功能Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料HIGD1A (HIG1 domain family member 1A), also known as HIG1 (hypoxia-inducible gene 1 protein) or HSPC010, is a 93 amino acid multi-pass membrane protein that contains one HIG1 domain. Existing as two alternatively spliced isoforms, the gene encoding HIGD1A maps to human chromosome 3, which contains approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

     

     

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