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- Bioss
- bs-13043P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-13043P |
| 英文名称 | DNAAF4 Antibody Blocking Peptide |
| 中文名称 | DYX1C1蛋白封闭多肽 |
| 英文别名 | Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Visual system Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Disease Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Glial Tags & Cell Markers > Cell Type Markers > Neuroscience Markers > Neuronal |
| 亚基 | Interacts with ESR1 and ESR2. Interacts with STUB1. |
| 亚细胞定位 | Nucleus. Cytoplasm. |
| 组织特异性 | Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells. |
| 相似性 | Contains 1 CS domain. Contains 3 TPR repeats. |
| 功能 | Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis. |
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DNAAF4 Antibody Blocking Peptide(bs-13043P)-500ug
￥880
