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500ug
| 产品编号 | bs-9010P |
| 英文名称 | DPP6 Antibody Blocking Peptide |
| 中文名称 | 二肽基肽酶6封闭多肽 |
| 英文别名 | Dipeptidyl aminopeptidase like protein 6; Dipeptidyl aminopeptidase related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV like protein; Dipeptidylpeptidase 6; Dipeptidylpeptidase VI; DPPX; DPP6_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Other Enzymes |
| 亚基 | Homodimer. Binds KCND2. |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein (Probable). |
| 组织特异性 | Expressed predominantly in brain. |
| 相似性 | Belongs to the peptidase S9B family. |
| 功能 | May be involved in the physiological processes of brain function. Has no dipeptidyl aminopeptidase activity. May modulate the cell surface expression and the activity of the potassium channel KCND2. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung. |
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DPP6 Antibody Blocking Peptide(bs-9010P)-500ug
¥880







