TESPA1 Antibody Blocking Peptide(bs-16981P)-500ug

TESPA1 Antibody Blocking Pepti

de(bs-16981P)-500ug
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  • ¥880
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  • bs-16981P
  • 2025年10月16日
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      500ug

    产品编号bs-16981P
    英文名称TESPA1 Antibody Blocking Peptide
    中文名称KIAA0748蛋白封闭多肽
    英文别名HSPC257; K0748_HUMAN; KIAA0748; TESPA1 – thymocyte expressed, positive selection associated 1; TESPA1; thymocyte expressed, positive selection associated 1; Uncharacterized protein KIAA0748.
    纯化方法HPLC
    亚基Interacts with PLCG1 and GRB2; the association is increased with prolonged stimulation of the TCR and may facilitate the assembly of the LAT signalosome. Interacts with ITPR1. Also interacts with ITPR3 (By similarity). Interacts with HSPA9.
    亚细胞定位Cytoplasm. Endoplasmic reticulum membrane.Note=May localize to mitochondria-associated endoplasmic reticulum membrane (MAM).
    翻译后修饰May be phosphorylated in response to store-operated Ca(+2) entry.
    功能Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

     

     

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