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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-16981P |
| 英文名称 | TESPA1 Antibody Blocking Peptide |
| 中文名称 | KIAA0748蛋白封闭多肽 |
| 英文别名 | HSPC257; K0748_HUMAN; KIAA0748; TESPA1 – thymocyte expressed, positive selection associated 1; TESPA1; thymocyte expressed, positive selection associated 1; Uncharacterized protein KIAA0748. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with PLCG1 and GRB2; the association is increased with prolonged stimulation of the TCR and may facilitate the assembly of the LAT signalosome. Interacts with ITPR1. Also interacts with ITPR3 (By similarity). Interacts with HSPA9. |
| 亚细胞定位 | Cytoplasm. Endoplasmic reticulum membrane.Note=May localize to mitochondria-associated endoplasmic reticulum membrane (MAM). |
| 翻译后修饰 | May be phosphorylated in response to store-operated Ca(+2) entry. |
| 功能 | Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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TESPA1 Antibody Blocking Peptide(bs-16981P)-500ug
¥880







