- ￥880
- Bioss
- bs-11684P
- 2025年10月16日
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- 详细信息
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500ug
| 产品编号 | bs-11684P |
| 英文名称 | NPEPPS Antibody Blocking Peptide |
| 中文名称 | 嘌呤霉素敏感性氨肽酶蛋白封闭多肽 |
| 英文别名 | PSAP; AAP-S; aminopeptidase puromycin sensitive; Cytosol alanyl aminopeptidase; METALLOPROTEASE 100; METALLOPROTEASE MP100; MP 100; MP100; Npepps; PSA; PSA_HUMAN; Puromycin sensitive aminopeptidase; Puromycin-sensitive aminopeptidase. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease > Tangles & Tau |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). |
| 相似性 | Belongs to the peptidase M1 family. |
| 功能 | Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Puromycin-sensitive aminopeptidase is a 100kDa zinc metallopeptidase which degrades neuropeptides by removing amino acid residues from the amino-terminus. The protein is the most abundant aminopeptidase in the brain, however it is not exclusive to that organ. It is localized primarily in the cytoplasm, and plays a role in the metabolism of neuropeptides in nerve terminals and synaptic clefts. The human PSA gene maps to chromosome 17q 2-32. |
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NPEPPS Antibody Blocking Peptide(bs-11684P)-500ug
￥880
