- ￥880
- Bioss
- bs-14189P
- 2025年10月16日
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500ug
| 产品编号 | bs-14189P |
| 英文名称 | CCBP2 Antibody Blocking Peptide |
| 中文名称 | 趋化因子结合蛋白2封闭多肽 |
| 英文别名 | ACKR2; Atypical chemokine receptor 2; C C chemokine receptor D6; CCBP2; ACKR2_HUMAN; CCR10; CCR9; Chemokine binding protein 2; Chemokine receptor CCR 10; Chemokine receptor CCR 9; Chemokine receptor D6; CMKBR9; D6; hD6. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Chemokines > Beta Chemokine Rec. (CCR) |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. |
| 翻译后修饰 | Phosphorylated on serine residues in the C-terminal cytoplasmic tail. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Chemokine Receptor D6 is a member of the C-C (β chemokine) G protein-coupled receptor family. This family is characterized by a pair of adjacent cysteine residues. C-C chemokine receptor family members also include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10, CCXCKR, Bonzo, BOB (brother of Bonzo) and Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to sites of inflammation. Chemokine Receptor D6 acts as a receptor for various C-C type chemokines, including SCYA2/MCP-1, SCY3/MIP-1-α, SCYA5/RANTES and SCYA7/MCP-3. It is expressed primarily in placental tissues and fetal liver, but is also detected in lymphatic endothelial cells, lymph nodes and mucosa of the small and large intestines. |
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CCBP2 Antibody Blocking Peptide(bs-14189P)-500ug
￥880
