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- Bioss
- bs-15474P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15474P |
| 英文名称 | HHAT Antibody Blocking Peptide |
| 中文名称 | T细胞2识别黑色素瘤抗原封闭多肽 |
| 英文别名 | 2810432O22Rik; AC115917.1; AI462858; FLJ10724; FLJ34867; Hedgehog acyltransferase; Hhat; HHAT_HUMAN; MART 2; MART-2; MART2; Melanoma antigen recognized by T cells 2; Melanoma antigen recognized by T-cells 2; MGC11697; OTTMUSP00000033669; Protein cysteine N palmitoyltransferase HHAT; Protein-cysteine N-palmitoyltransferase HHAT; RGD1311746; SKI1; Skinny hedgehog protein 1; Skinny hedgehog protein; Skn. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with SHH (By similarity). |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). |
| 组织特异性 | Ubiquitously expressed in normal tissues and cancer cell lines. |
| 相似性 | Belongs to the membrane-bound acyltransferase family. HHAT subfamily. |
| 功能 | Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1. |
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HHAT Antibody Blocking Peptide(bs-15474P)-500ug
￥880
