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500ug
| 产品编号 | bs-0190P |
| 英文名称 | PACAP Antibody Blocking Peptide |
| 中文名称 | 腺苷酸环化酶激活肽-27/38封闭多肽 |
| 英文别名 | Adenylate Cyclase Activating Polypeptide 1 (Pituitary); Prepro-PACAP; PACAP; Pituitary Adenylate Cyclase Activating Polypeptide; PRP-48; PACAP27; PACAP38; ADCYAP1; PACA_HUMAN; |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Cell Biology > Apoptosis > Intracellular > Caspases etc > Caspases Neuroscience > Neurotransmitter > Neuropeptides > Hormones |
| 亚基 | Interacts with ADCYAP1R1 (via N-terminal extracellular domain). |
| 亚细胞定位 | Extracellular region or secreted |
| 相似性 | Belongs to the glucagon family. |
| 功能 | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] |
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PACAP Antibody Blocking Peptide(bs-0190P)-500ug
¥880








