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500ug
| 产品编号 | bs-0898P |
| 英文名称 | FABP2 Antibody Blocking Peptide |
| 中文名称 | 小肠型脂肪酸结合蛋白封闭多肽 |
| 英文别名 | FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; I FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; OTTHUMP00000163925. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Binding proteins Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism Developmental Biology > Lineage specification > Endoderm Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation Signal Transduction > Metabolism > Lipid metabolism Stem Cells > Lineage Markers > Endoderm |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. |
| 相似性 | Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| 功能 | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008] |
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FABP2 Antibody Blocking Peptide(bs-0898P)-500ug
¥880







