- ￥880
- Bioss
- bs-21209P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21209P |
| 英文名称 | SLC22A16 Antibody Blocking Peptide |
| 中文名称 | 溶质载体家族22成员15封闭多肽 |
| 英文别名 | Flipt 1; FLIPT1; Fly like putative organic ion transporter 1; Fly like putative transporter 1; Fly-like putative transporter 1; PRO34686; S22AF_HUMAN; slc22a15; Solute carrier family 22 (organic cation transporter) member 15; Solute carrier family 22 member 15; Trans like protein. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell Membrane. |
| 组织特异性 | Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. Expressed in testis and epididymis (at protein level). Expressed at lower levels in bone marrow and fetal liver. Expressed in hematopoietic cells, including CD34+ leukocytes and leukemia cells. Abundantly expressed in ovarian cancer clear-cell adenocarcinoma. Expressed in endometrium (at protein level); highly expressed during the normal secretory phase, but expression is significantly reduced in the proliferative phase. |
| 相似性 | Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. |
| 功能 | High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011] |
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SLC22A16 Antibody Blocking Peptide(bs-21209P)-500ug
￥880
