- ￥880
- Bioss
- bs-15374P
- 2026年10月10日
企业认证
相关产品推荐更多 >
Capn2 | Calpain-2 Ab Blocking Peptide(bs-1599P)-500ug
￥880
rMu Tcl1a | Tcl1 Protein, N-His(bs-106508P)-20ug/50ug/100ug
￥980
B.taurus (Bo) ALB | BSA, BF680 conj.(bs-0292P-BF680)-100ug/1mg
￥880LILRB5 | CD85c/LIR8 Ab Blocking Peptide(bs-2658P)-500ug
￥880rHu CLGN | Calmegin Protein, N-His(bs-104754P)-20ug/50ug/100ug
￥980
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
AI 赋能培养基定制开发：CHO 培养基是如何实现产量提升Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15374P |
| 英文名称 | GPCR TGR7 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶联受体TGR7蛋白封闭多肽 |
| 英文别名 | Beta-alanine receptor; G-protein coupled receptor TGR7; Mas-related G-protein coupled receptor member D; MRGD; MRGPRD; MRGRD; TGR7; MRGRD_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Sensory System > Somatosensory system > Nociception Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. Mas subfamily. |
| 功能 | May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mas-related G protein-coupled receptors are sensory neuron-specific G protein-coupled receptors that are usually involved in the development and function of nociceptive neurons and may also regulate the sensation or modulation of pain. MRGD (MAS-related GPR, member D), also known as MRGPRD or TGR7, is a 321 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family and the Mas subfamily. MRGD is suggested to function specifically as a receptor for beta-alanine, a naturally occurring beta amino acid. Beta-alanine induces Ca2+ influx and decreases forskolin-stimulated cAMP production in cells expressing MRGD. Neurons of outer epidermis that express MRGD act as nociceptors in which they respond indirectly to external stimuli by detecting ATP release in the skin. MRGD is encoded by a gene located on human chromosome 11q13.2. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
MRGPRD | TGR7 Ab Blocking Peptide(bs-15374P)-500ug
￥880
