- ￥880
- Bioss
- bs-11514P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11514P |
| 英文名称 | CCKAR Antibody Blocking Peptide |
| 中文名称 | 胆囊收缩素A受体封闭多肽 |
| 英文别名 | CCK A; CCK A receptor; CCK AR; CCK-AR; CCKAR_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Cancer Metabolism > Types of disease > Neurodegenerative disease Metabolism > Types of disease > Obesity Neuroscience > Neurology process > Metabolism Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CCKAR Antibody Blocking Peptide(bs-11514P)-500ug
￥880
