CABP4 Ab Blocking Peptide(bs-11980P)-500ug产品图

CABP4 Ab Blocking Peptide(bs-1

1980P)-500ug
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  • bs-11980P
  • 2026年10月10日
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    产品编号bs-11980P
    英文名称CABP4 Antibody Blocking Peptide
    中文名称瞬时受体电位通道蛋白4封闭多肽
    英文别名CABP 4; CaBP4; CABP4_HUMAN; Calcium binding protein 4; Calcium-binding protein 4; CSNB 2B; CSNB2B.
    纯化方法HPLC
    亚细胞定位Cytoplasm. Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.Target information above from: UniProt accession P57796 The UniProt Consortium_x000D_ The Universal Protein Resource (UniProt) in 2010_x000D_ Nucleic Acids Res. 38:D142-D148 (2010). _x000D_ _x000D_ Information by UniProt
    组织特异性Expressed in retina and in the inner hair cells (IHC) of the cochlea.
    翻译后修饰Phosphorylated. Phosphorylation levels change with the light conditions and regulate the activity.
    相似性Contains 4 EF-hand domains.
    功能Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The calcium binding protein (CaBP) family shares much similarity to calmodulin. It has been shown that CaBP proteins can substitute functionally for, and probably augment the function of, calmodulin. Calcium binding proteins are a crucial part of calcium mediated cellular signal transduction in the central nervous system. There are several members of the family with varying expression patterns. CaBP1 and CaBP2 can be expressed as multiple, alternatively spliced variants in brain and retina. CaBP3, CaBP4 and CaBP 5 are restricted to retinal rod and cone cells.

     

     

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