- ￥880
- Bioss
- bs-13923P
- 2025年10月16日
企业认证
相关产品推荐更多 >
DPCR1 Antibody Blocking Peptide(bs-20005P)-500ug
￥880
MMS2/EDPF1 Antibody Blocking Peptide(bs-9377P)-500ug
￥880ZCCHC24/C10orf56 Antibody Blocking Peptide(bs-18551P)-500ug
￥880Phospho-Zap-70 (Tyr493) Antibody Blocking Peptide(bs-3479P)-500ug
￥1080WEE1 protein Antibody Blocking Peptide(bs-23526P)-500ug
￥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13923P |
| 英文名称 | Chp2 Antibody Blocking Peptide |
| 中文名称 | 钙调磷酸酶B相关蛋白2封闭多肽 |
| 英文别名 | Calcineurin B homologous protein 2; HCA520; CHP2_HUMAN; Hepatocellular carcinoma associated antigen 520. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with PPP3CA. Interacts with SLC9A1/NHE1; the interaction occurs in a calcium-dependent manner. |
| 亚细胞定位 | Nucleus. Cytoplasm. Cell membrane. Note=Predominantly localized in a juxtanuclear region. Colocalizes with SLC9A3 in the juxtanuclear region and at the plasma membrane (By similarity). Exported from the nucleus to the cytoplasm through a nuclear export signal (NES) pathway. May shuttle between nucleus and cytoplasm. |
| 组织特异性 | Expressed in malignantly transformed cells butvnot detected in normal tissues. |
| 相似性 | Belongs to the calcineurin regulatory subunit family. CHP subfamily. Contains 4 EF-hand domains. |
| 功能 | Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Chp2 binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. It is expressed in malignantly transformed cells but not detected in normal tissues. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Chp2 Antibody Blocking Peptide(bs-13923P)-500ug
￥880
