CPSF1 Antibody Blocking Peptide(bs-14035P)-500ug

CPSF1 Antibody Blocking Peptid

e(bs-14035P)-500ug
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  • bs-14035P
  • 2025年10月16日
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      500ug

    产品编号bs-14035P
    英文名称CPSF1 Antibody Blocking Peptide
    中文名称剪切及多聚腺苷酸化特异因子蛋白1封闭多肽
    英文别名Cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF160; HSU37012; P/cl.18.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing

    亚细胞定位Nucleus, nucleoplasm.
    翻译后修饰The N-terminus is blocked.
    相似性Belongs to the CPSF1 family.
    功能CPSF1 (Cleavage and polyadenylation specificity factor subunit 1) is a component of the cleavage and polyadenylation specificity factor (CPSF) complex. It plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]

     

     

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