HSD17B14 Antibody Blocking Peptide(bs-16527P)-500ug

HSD17B14 Antibody Blocking Pep

tide(bs-16527P)-500ug
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  • bs-16527P
  • 2025年10月16日
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      500ug

    产品编号bs-16527P
    英文名称HSD17B14 Antibody Blocking Peptide
    中文名称17β羟类固醇脱氢酶14/17β-HSD14封闭多肽
    英文别名17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; DHRS10; DHB14_HUMAN; Retinal short chain dehydrogenase/reductase 3; Retinal short chain dehydrogenase/reductase retSDR3; retSDR3; SDR3.
    纯化方法HPLC
    研究领域

    Signal Transduction > Growth Factors/Hormones > Hormones

    Signal Transduction > Metabolism > Lipid metabolism

    亚基Homotetramer.
    亚细胞定位Cytoplasmic
    组织特异性Highly expressed in brain, placenta, liver and kidney.
    相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    功能HSD17B14 belongs to the short-chain dehydrogenases/reductases (SDR) family. It has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity and converts oestradiol to oestrone. The physiological substrate is not known. HSD17B14 acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). It is highly expressed in brain, placenta, liver and kidney.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]

     

     

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