- ￥880
- Bioss
- bs-14003P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-14003P |
| 英文名称 | COX11 Antibody Blocking Peptide |
| 中文名称 | 细胞色素c氧化酶11封闭多肽 |
| 英文别名 | COX11; COX11 homolog; COX11 homolog, cytochrome c oxidase assembly protein (yeast); COX11_HUMAN; COX11P; Cytochrome c oxidase assembly protein COX11; Cytochrome c oxidase assembly protein COX11, mitochondrial; Cytochrome c oxidase subunit 11; mitochondrial. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Metabolism > Mitochondrial Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria |
| 亚基 | Interacts with CNNM4/ACDP4. |
| 亚细胞定位 | Mitochondrion inner membrane. |
| 组织特异性 | Ubiquitous. |
| 相似性 | Belongs to the COX11/CtaG family. |
| 功能 | Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in RhoDOBacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009] |
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COX11 Antibody Blocking Peptide(bs-14003P)-500ug
￥880
