- ￥880
- Bioss
- bs-18649P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-18649P |
| 英文名称 | MAN2C1 Antibody Blocking Peptide |
| 中文名称 | 甘露糖苷酶α胞浆封闭多肽 |
| 英文别名 | alpha D mannoside mannohydrolase; alpha mannosidase 2C1; Alpha mannosidase 6A8B; Alpha-D-mannoside mannohydrolase; Alpha-mannosidase 2C1; MA2C1_HUMAN; Man2c1; MAN6A8; MANA; MANA1; Mannosidase alpha 6A8; Mannosidase alpha A cytoplasmic; Mannosidase alpha class 2C member 1. |
| 纯化方法 | HPLC |
| 相似性 | Belongs to the glycosyl hydrolase 38 family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Misfolded glycoproteins are deglycosylated by the peptide N-glycanase during the degradation process. Free oligosaccharides released by N-glycanase are catabolized by cytosolic MAN2C1, also designated alpha-mannosidase 2C1. MAN2C1, a member of the glycosyl hydrolase 38 family, can cleave alpha 1,2-linked, alpha 1,3-linked and alpha 1,6-linked mannose residues and is stimulated by cobalt. The furanose analogs, swainsonine (SW) and 1,4-dideoxy-1,4-imino-d-mannitol (DIM), are known inhibitors of MAN2C1. The inhibition of MAN2C1 can enhance the adhesion of Jurkat T cells, showing a cytoskeletal rearrangement of the cells. |
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MAN2C1 Antibody Blocking Peptide(bs-18649P)-500ug
￥880
