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- 规格:
500ug
| 产品编号 | bs-11408P |
| 英文名称 | MC2R Antibody Blocking Peptide |
| 中文名称 | 促肾上腺皮质激素受体 |
| 英文别名 | ACTH receptor; ACTH-R; ACTHR; ACTHR_HUMAN; Adrenocorticotropic hormone receptor; Adrenocorticotropin receptor; Corticotropin receptor; MC2 receptor; MC2-R; MC2R; Melanocortin 2 receptor (adrenocorticotropic hormone); Melanocortin 2 receptor; Melanocortin receptor 2. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism Metabolism > Types of disease > Cancer Neuroscience > Endocrine system > Gonadotrophic axis Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | Interacts with FALP/MRAP. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Melanocytes and corticoadrenal tissue. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. |
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MC2R Antibody Blocking Peptide(bs-11408P)-500ug
¥880







