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500ug
| 产品编号 | bs-16711P |
| 英文名称 | TCOF1 Antibody Blocking Peptide |
| 中文名称 | 特雷彻·柯林斯综合征/下颔骨颜面发育不全相关蛋白封闭多肽 |
| 英文别名 | MFD1; TCOF 1; TCOF_HUMAN; TCOF1; Treacher Collins syndrome protein; Treacle; Treacle protein. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Nuclear Import / Export |
| 亚细胞定位 | Nucleus, nucleolus. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Contains 1 LisH domain. |
| 功能 | May be involved in nucleolar-cytoplasmic transport. May play a fundamental role in early embryonic development, particularly in development of the craniofacial complex. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
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TCOF1 Antibody Blocking Peptide(bs-16711P)-500ug
¥880







