- ￥880
- Bioss
- bs-4835P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-4835P |
| 英文名称 | MAL Antibody Blocking Peptide |
| 中文名称 | MAL蛋白封闭多肽 |
| 英文别名 | MAL; mal; MAL protein gene; Mal T-cell differentiation protein; MAL_HUMAN; MALGENE; MPV17; Myelin and lymphocyte protein; T-cell differentiation protein MAL; T-lymphocyte maturation-associated protein; VIP17. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Associated Proteins Cell Biology > Cell Cycle > Cell differentiation Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in the intermediate and late stages of T-cell differentiation. |
| 翻译后修饰 | Lipoprotein. |
| 相似性 | Belongs to the MAL family.
Contains 1 MARVEL domain. |
| 功能 | Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MAL (myelin and lymphocyte protein), also known as T lymphocyte maturation-associated protein, is a nonglycosylated hydrophobic integral membrane protein belonging to the Myelin and lymphocyte (MAL) family of proteolipids. MAL is highly enriched in nervous system myelin and in rafts and apical membranes of epithelial cells. It is involved in forming, stabilizing and maintaining glycosphingolipid-enriched membrane microdomains. MAL maintains the myelin sheath and, by controlling the sorting and trafficking of oligodendrocytes, it is involved in central nervous system paranode maintenance. MAL is a component of lipid rafts in myelinating cells. Association with glycosphingolipids may result in protein-lipid microdomain formation in myelin. MAL has been localized to the endoplasmic reticulum of T cells and in compact myelin of cells in the nervous system. MAL is primarily expressed by oligodendrocytes and Schwann cells in the intermediate and late stages of T cell differentiation. |
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MAL Antibody Blocking Peptide(bs-4835P)-500ug
￥880
