5-HTR4 Antibody Blocking Peptide(bs-2127P)-500ug

5-HTR4 Antibody Blocking Pepti

de(bs-2127P)-500ug
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  • bs-2127P
  • 2025年10月16日
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      500ug

    产品编号bs-2127P
    英文名称5-HTR4 Antibody Blocking Peptide
    中文名称5-羟色胺受体4封闭多肽
    英文别名5-HTR4 (5-hydroxytryptamine (serotonin) receptor 4a); Htr4a; 5-HT4; 5-HT4A; 5HT4; Htr45 HT 4; 5 HT4; 5 HT4R; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 hydroxytryptamine serotonin receptor 4; 5 hydroxytryptamine4 receptor; 5HT4; 5HT4R; Cardiac 5 HT4 receptor; HTR 4; HTR4; Serotonin 5 HT4 receptor; Serotonin receptor 4; 5HT4R_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Metabolism > Types of disease > Obesity

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Serotonin Receptors

    亚基Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR.
    亚细胞定位Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.
    组织特异性soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]

     

     

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