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500ug
| 产品编号 | bs-2127P |
| 英文名称 | 5-HTR4 Antibody Blocking Peptide |
| 中文名称 | 5-羟色胺受体4封闭多肽 |
| 英文别名 | 5-HTR4 (5-hydroxytryptamine (serotonin) receptor 4a); Htr4a; 5-HT4; 5-HT4A; 5HT4; Htr45 HT 4; 5 HT4; 5 HT4R; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 hydroxytryptamine serotonin receptor 4; 5 hydroxytryptamine4 receptor; 5HT4; 5HT4R; Cardiac 5 HT4 receptor; HTR 4; HTR4; Serotonin 5 HT4 receptor; Serotonin receptor 4; 5HT4R_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Obesity Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Serotonin Receptors |
| 亚基 | Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. |
| 组织特异性 | soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] |
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5-HTR4 Antibody Blocking Peptide(bs-2127P)-500ug
¥880







