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- Bioss
- bs-9548P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-9548P |
| 英文名称 | FNTB Antibody Blocking Peptide |
| 中文名称 | 法尼基转移酶β-亚单位封闭多肽 |
| 英文别名 | CAAX farnesyltransferase subunit beta; EC 2.5.1.58; EC=2.5.1.58; Farnesyltransferase; farnesyltransferase CAAX box beta1; farnesyltransferase, CAAX box, beta; FNTB; FNTB_HUMAN; FPTB; FTase beta; FTase-beta; Protein farnesyltransferase subunit beta; RAS proteins prenyltransferase beta; Ras proteins prenyltransferase subunit beta. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Amino Acids |
| 亚基 | Heterodimer of an alpha and a beta subunit. |
| 相似性 | Belongs to the protein prenyltransferase subunit beta family. Contains 5 PFTB repeats. |
| 功能 | Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Alpha and beta subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The beta subunit, which is known as FT beta, CAAX farnesyltransferase subunit beta, or Ras proteins prenyltransferase subunit beta, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Alpha subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate. |
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FNTB Antibody Blocking Peptide(bs-9548P)-500ug
￥880
