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- Bioss
- bs-10692P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-10692P |
| 英文名称 | MIA2 Antibody Blocking Peptide |
| 中文名称 | 黑色素瘤抑制活性蛋白2封闭多肽 |
| 英文别名 | Melanoma inhibitory activity 2; Melanoma inhibitory activity protein 2; Mia2; MIA2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors Cancer > Tumor immunology > Cytokines Immunology > Innate Immunity > Cytokines |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. |
| 相似性 | Belongs to the MIA/OTOR family. Contains 1 SH3 domain. |
| 功能 | May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cutaneous T cell lymphomas (CTCL) represent a group of malignancies that originate from CD4-T lymphocytes and manifest on the skin. CTCL is a general term for several neoplasms including mycosis fungoides, T cell leukemia/ lymphoma and pagetoid reticulosis, all of which are very difficult to treat in the advanced stages. CTAGE2 (cutaneous T cell lymphoma associated-antigen 2) is a member of the cancer/testis antigen family of proteins (CTAGE) that, under normal conditions, are found primarily in the testis with little or no expression in other parts of the body. Another member of the CTAG family, namely CTAGE5 (also known as MEA11, MEA6, MGEA11 or MGEA6), is a tumor associated antigen that is found in tumors of various origins, including cutaneous T cell lymphomas. Both CTAGE2 and CTAGE5 are expressed as multiple isoforms due to alternative splicing events. |
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MIA2 Antibody Blocking Peptide(bs-10692P)-500ug
￥880
