- ￥880
- Bioss
- bs-12580P
- 2025年10月16日
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500ug
| 产品编号 | bs-12580P |
| 英文名称 | ARID3B Antibody Blocking Peptide |
| 中文名称 | 神经母细胞瘤相关蛋白ARID3B封闭多肽 |
| 英文别名 | BDP / ARID3B; ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright and dead ringer gene product homologous protein Bdp; Bright and dead ringer protein; Bright like; Bright-like protein; Brightlike; DRIL2. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules Epigenetics and Nuclear Signaling > Transcription > Other factors Stem Cells > Embryonic Stem Cells > Intracellular |
| 亚基 | Heterodimer with ARID3A. Interacts with unphosphorylated RB1. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level). |
| 相似性 | Contains 1 ARID domain. Contains 1 REKLES domain. |
| 功能 | Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma. |
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ARID3B Antibody Blocking Peptide(bs-12580P)-500ug
￥880
