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- bs-9565P
- 2025年10月16日
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500ug
| 产品编号 | bs-9565P |
| 英文名称 | SLC18A2 Antibody Blocking Peptide |
| 中文名称 | 脑单胺类神经递质转运蛋白封闭多肽 |
| 英文别名 | MNAT; Monoamine neurotransmitter transporter; Monoamine transporter; Slc18a2; Solute carrier family 18 (vesicular monoamine) member 2; Solute carrier family 18 member 2; SVAT; SVMT; Synaptic vesicle amine transporter brain; Synaptic vesicle monoamine transporter brain; Synaptic vesicular amine transporter; VAT 2; VAT2; Vesicle monoamine transporter type 2; Vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2; VMAT 2; VMAT2; VMAT2_HUMAN; 1110037L13Rik; 9330105E13; MGC120477; MGC120478; MGC26538; MGC90556. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease Neuroscience > Neurotransmission > Secretory Vesicles Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine Neuroscience > Neurotransmitter > Biogenic Amines > Histamine Neuroscience > Neurotransmitter > Biogenic Amines > Noradrenaline Neuroscience > Neurotransmitter > Biogenic Amines > Serotonin / 5HT Neuroscience > Neurotransmitter > Transporters > Dopamine Neuroscience > Neurotransmitter > Transporters > Other Transporters |
| 亚基 | Interacts with SLC6A3. |
| 亚细胞定位 | Cytoplasmic vesicle membrane. |
| 相似性 | Belongs to the major facilitator superfamily. Vesicular transporter family. |
| 功能 | Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism. |
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SLC18A2 Antibody Blocking Peptide(bs-9565P)-500ug
￥880
